Gene

ces2b

ID
ZDB-GENE-041014-96
Name
carboxylesterase 2b
Symbol
ces2b Nomenclature History
Previous Names
  • si:ch211-93f2.1
  • wu:fb62a02
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have carboxylic ester hydrolase activity. Predicted to localize to extracellular space. Is expressed in gut; intestinal bulb; and liver.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ces2b Human Ortholog
No data available
Associated With ces2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR019826 Carboxylesterase type B, active site
Conserved_site IPR019819 Carboxylesterase type B, conserved site
Domain IPR002018 Carboxylesterase, type B
Family IPR050309 Type-B Carboxylesterase/Lipase
Homologous_superfamily IPR029058 Alpha/Beta hydrolase fold
Domain Details Per Protein
Protein Length Alpha/Beta hydrolase fold Carboxylesterase, type B Carboxylesterase type B, active site Carboxylesterase type B, conserved site Type-B Carboxylesterase/Lipase
UniProtKB:A0A8M9PZ17 1611
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ces2b-202 (1) Ensembl 723 nt
mRNA ces2b-203 (1) Ensembl 834 nt
mRNA si:ch211-93f2.1-201 (1) Ensembl 2,891 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Note
According to ZDB-PUB-210305-10, neighbor-joining phylogenetic tree showed that the sequence of si:ch211-93f2.1 was dissimilar from cholinesterase across 26 species (Fig. 4d), indicating that BChE-like protein in zebrafish is an atypical cholinesterase and si:ch211-93f2.1 has a unique evolutionary origin.
Citations