Gene
flvcr1
- ID
- ZDB-GENE-041014-359
- Name
- FLVCR choline and heme transporter 1
- Symbol
- flvcr1 Nomenclature History
- Previous Names
-
- si:ch211-147d7.6
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable heme binding activity and heme transmembrane transporter activity. Acts upstream of or within erythrocyte differentiation and heme metabolic process. Predicted to be located in membrane. Predicted to be active in mitochondrion. Orthologous to human FLVCR1 (FLVCR heme transporter 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Mercurio et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| neurodevelopmental disorder with microcephaly, absent speech, and hypotonia | Alliance | Neurodevelopmental disorder with microcephaly, absent speech, and hypotonia | 621060 |
| Retinopathy-sensory neuropathy syndrome | 609033 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Choline/ethanolamine transporter FLVCR1-2/SLC49-like | Major facilitator superfamily | Major facilitator superfamily domain | MFS transporter superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q5RGT2
|
527 | ||||
|
UniProtKB:A0A8M2B7P0
|
525 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
flvcr1-201
(1)
|
Ensembl | 2,644 nt |
Interactions and Pathways
No data available
Plasmids
No data available