Gene
adgrg6
- ID
- ZDB-GENE-041014-357
- Name
- adhesion G protein-coupled receptor G6
- Symbol
- adgrg6 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Exhibits G protein-coupled receptor activity; collagen binding activity; and extracellular matrix binding activity. Involved in several processes, including animal organ morphogenesis; cAMP-mediated signaling; and myelination. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Is expressed in several structures, including head; otic vesicle; pericardial region; pleuroperitoneal region; and sensory system. Orthologous to human ADGRG6 (adhesion G protein-coupled receptor G6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1654 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- 50 figures from 18 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Lethal congenital contracture syndrome 9 | 616503 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000203 | GPS motif |
| Conserved_site | IPR017983 | GPCR, family 2, secretin-like, conserved site |
| Domain | IPR000859 | CUB domain |
| Domain | IPR017981 | GPCR, family 2-like, 7TM |
| Family | IPR000832 | GPCR, family 2, secretin-like |
| Family | IPR001759 | Pentraxin-related |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR035914 | Spermadhesin, CUB domain superfamily |
| Homologous_superfamily | IPR046338 | GAIN domain superfamily |
Domain Details Per Protein
| Protein | Length | Concanavalin A-like lectin/glucanase domain superfamily | CUB domain | GAIN domain superfamily | GPCR, family 2-like, 7TM | GPCR, family 2, secretin-like | GPCR, family 2, secretin-like, conserved site | GPS motif | Pentraxin-related | Spermadhesin, CUB domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:C6KFA3
|
1185 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adgrg6-201
(1)
|
Ensembl | 3,558 nt | ||
| mRNA |
adgrg6-202
(1)
|
Ensembl | 796 nt | ||
| mRNA |
adgrg6-203
(1)
|
Ensembl | 516 nt | ||
| mRNA |
adgrg6-204
(1)
|
Ensembl | 4,246 nt |
Interactions and Pathways
No data available
Plasmids
No data available