Gene
vash2
- ID
- ZDB-GENE-041014-355
- Name
- vasohibin 2
- Symbol
- vash2 Nomenclature History
- Previous Names
-
- si:ch211-147d7.1
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable tubulin-tyrosine carboxypeptidase. Predicted to be involved in regulation of angiogenesis. Predicted to act upstream of or within proteolysis. Predicted to be active in cytoplasm. Is expressed in musculature system; pharyngeal arch; segmental plate; somite; and telencephalon. Orthologous to human VASH2 (vasohibin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1662 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR028131 | Tubulinyl-Tyr carboxypeptidase |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Tubulinyl-Tyr carboxypeptidase |
|---|---|---|---|
| UniProtKB:A0A8M2B7N9 | InterPro | 370 | |
| UniProtKB:Q5RGT1 | InterPro | 348 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-147D7 | ZFIN Curated Data | |
| Contained in | BAC | CH211-181H6 | ZFIN Curated Data | |
| Encodes | EST | eu1662 | Thisse et al., 2005 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001025523 (1) | 1047 nt | ||
| Genomic | GenBank:BX664628 (1) | 101135 nt | ||
| Polypeptide | UniProtKB:A0A8M2B7N9 (1) | 370 aa |
- Yin, H.M., Yan, L.F., Liu, Q., Peng, Z., Zhang, C.Y., Xia, Y., Su, D., Gu, A.H., Zhou, Y. (2020) Activating transcription factor 3 coordinates differentiation of cardiac and hematopoietic progenitors by regulating glucose metabolism. Science advances. 6:eaay9466
- Ma, Y., Zang, L., Wang, D., Jiang, J., Wang, C., Wang, X., Fang, F., Wang, H. (2019) Effects of miR-181a-5p abnormal expression on zebrafish (Danio rerio) vascular development following triclosan exposure. Chemosphere. 223:523-535
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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