Gene

pycr3

ID
ZDB-GENE-041014-244
Name
pyrroline-5-carboxylate reductase 3
Symbol
pycr3 Nomenclature History
Previous Names
  • pycrl
  • si:dkey-235d18.3
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to enable pyrroline-5-carboxylate reductase activity. Predicted to be involved in L-proline biosynthetic process. Predicted to act upstream of or within proline biosynthetic process. Predicted to be located in cytosol. Orthologous to human PYCR3 (pyrroline-5-carboxylate reductase 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Kuo et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa16640Allele with one point mutationUnknownSplice SiteENU
sa25147Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-pycr3N/AKuo et al., 2016
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Human Disease
Associated With pycr3 Human Ortholog
No data available
Associated With pycr3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR053790 Pyrroline-5-carboxylate reductase-like conserved site
Domain IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal
Domain IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain
Family IPR000304 Pyrroline-5-carboxylate reductase-like
Homologous_superfamily IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
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Domain Details Per Protein
Protein Length 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily NAD(P)-binding domain superfamily Pyrroline-5-carboxylate reductase, catalytic, N-terminal Pyrroline-5-carboxylate reductase, dimerisation domain Pyrroline-5-carboxylate reductase-like Pyrroline-5-carboxylate reductase-like conserved site
UniProtKB:Q5SPD7 288
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 20
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA pycr3-201 (1) Ensembl 1,908 nt
mRNA pycr3-202 (1) Ensembl 859 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-235D18ZFIN Curated Data
EncodescDNAMGC:162762ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanPYCR38
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MousePycr315
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
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