Gene
pak6b
- ID
- ZDB-GENE-041014-121
- Name
- p21 protein (Cdc42/Rac)-activated kinase 6b
- Symbol
- pak6b Nomenclature History
- Previous Names
-
- pak6 (1)
- si:ch211-158b22.3
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Predicted to be involved in several processes, including activation of protein kinase activity; signal transduction by protein phosphorylation; and stress-activated protein kinase signaling cascade. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma. Orthologous to several human genes including BUB1B-PAK6 (BUB1B-PAK6 readthrough).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Binding_site | IPR017441 | Protein kinase, ATP binding site |
Domain | IPR000095 | CRIB domain |
Domain | IPR000719 | Protein kinase domain |
Domain | IPR033923 | p21 activated kinase binding domain |
Domain | IPR035066 | Serine/threonine-protein kinase PAK 6, catalytic domain |
Family | IPR050285 | STE20 Serine/Threonine-Protein Kinase |
Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Homologous_superfamily | IPR036936 | CRIB domain superfamily |
Domain Details Per Protein
Protein | Length | CRIB domain | CRIB domain superfamily | p21 activated kinase binding domain | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase PAK 6, catalytic domain | STE20 Serine/Threonine-Protein Kinase |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:A5PEY8
|
607 |
Interactions and Pathways
No data available
Plasmids
No data available