Gene
pak6b
- ID
- ZDB-GENE-041014-121
- Name
- p21 protein (Cdc42/Rac)-activated kinase 6b
- Symbol
- pak6b Nomenclature History
- Previous Names
-
- pak6 (1)
- si:ch211-158b22.3
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction; protein phosphorylation; and regulation of MAPK cascade. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma. Orthologous to several human genes including PAK6 (p21 (RAC1) activated kinase 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000095 | CRIB domain |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR033923 | p21 activated kinase binding domain |
| Domain | IPR035066 | Serine/threonine-protein kinase PAK 6, catalytic domain |
| Family | IPR050285 | STE20 Serine/Threonine-Protein Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036936 | CRIB domain superfamily |
Domain Details Per Protein
| Protein | Length | CRIB domain | CRIB domain superfamily | p21 activated kinase binding domain | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase PAK 6, catalytic domain | STE20 Serine/Threonine-Protein Kinase |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A5PEY8
|
607 |
Interactions and Pathways
No data available
Plasmids
No data available