Gene

mettl1

ID
ZDB-GENE-041010-24
Name
methyltransferase 1, tRNA methylguanosine
Symbol
mettl1 Nomenclature History
Previous Names
  • zgc:103636 (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have tRNA (guanine-N7-)-methyltransferase activity. Predicted to be involved in RNA (guanine-N7)-methylation and tRNA methylation. Predicted to localize to nucleus and tRNA methyltransferase complex. Orthologous to human METTL1 (methyltransferase like 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mettl1 Human Ortholog
No data available
Associated With mettl1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type
Family IPR025763 tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote
Homologous_superfamily IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
Domain Details Per Protein
Protein Length S-adenosyl-L-methionine-dependent methyltransferase superfamily tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote tRNA (guanine-N-7) methyltransferase, Trmb type
UniProtKB:Q5XJ57 241
UniProtKB:B2GRE1 241
UniProtKB:A0A8M2B2M5 194
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mettl1-201 (1) Ensembl 860 nt
mRNA mettl1-202 (1) Ensembl 937 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations