Gene
pcyt2
- ID
- ZDB-GENE-041010-132
- Name
- phosphate cytidylyltransferase 2, ethanolamine
- Symbol
- pcyt2 Nomenclature History
- Previous Names
-
- im:7158585
- wu:fb39h11
- zgc:103434 (1)
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable ethanolamine-phosphate cytidylyltransferase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to act upstream of or within phospholipid biosynthetic process. Predicted to be active in cytoplasm. Is expressed in central nervous system; cranial ganglion; epiphysis; and ventral mesoderm. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 82. Orthologous to human PCYT2 (phosphate cytidylyltransferase 2, ethanolamine).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103434 (12 images)
- IMAGE:7158585 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 82 | Alliance | Spastic paraplegia 82, autosomal recessive | 618770 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | CTP:phosphocholine cytidylyltransferase domain | Cytidyltransferase-like domain | Ethanolamine-phosphate cytidylyltransferase | Rossmann-like alpha/beta/alpha sandwich fold |
|---|---|---|---|---|---|
|
UniProtKB:Q5XJC6
|
397 |
Interactions and Pathways
No data available
Plasmids
No data available