Gene
pcyt2
- ID
- ZDB-GENE-041010-132
- Name
- phosphate cytidylyltransferase 2, ethanolamine
- Symbol
- pcyt2 Nomenclature History
- Previous Names
-
- im:7158585
- wu:fb39h11
- zgc:103434 (1)
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have catalytic activity. Predicted to be involved in biosynthetic process. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia. Is expressed in central nervous system; cranial ganglion; epiphysis; and ventral mesoderm. Orthologous to human PCYT2 (phosphate cytidylyltransferase 2, ethanolamine).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103434 (12 images)
- IMAGE:7158585 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 82 | Alliance | Spastic paraplegia 82, autosomal recessive | 618770 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | CTP:phosphocholine cytidylyltransferase domain | Cytidyltransferase-like domain | Ethanolamine-phosphate cytidylyltransferase | Rossmann-like alpha/beta/alpha sandwich fold |
|---|---|---|---|---|---|
|
UniProtKB:Q5XJC6
|
397 |
Interactions and Pathways
No data available
Plasmids
No data available