Gene
ccnd3
- ID
- ZDB-GENE-041010-110
- Name
- cyclin D3
- Symbol
- ccnd3 Nomenclature History
- Previous Names
-
- zgc:103502 (1)
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in G1/S transition of mitotic cell cycle and positive regulation of G1/S transition of mitotic cell cycle. Predicted to act upstream of or within cell division. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytoplasm; microtubule organizing center; and nucleus. Is expressed in brain. Orthologous to human CCND3 (cyclin D3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103502 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cyclin | Cyclin, C-terminal domain | Cyclin-like domain | Cyclin-like superfamily | Cyclin, N-terminal | Cyclins, cyclin-box |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q5XJ98 | InterPro | 277 | ||||||
| UniProtKB:A0AB32THL8 | InterPro | 276 |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | RP71-11B17 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:103502 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:191169 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001006017 (1) | 1273 nt | ||
| Genomic | GenBank:AL645789 (1) | 167635 nt | ||
| Polypeptide | UniProtKB:Q5XJ98 (1) | 277 aa |
- Ding, Q., Hao, Q., Zhang, Q., Yang, Y., Olsen, R.E., Ringø, E., Ran, C., Zhang, Z., Zhou, Z. (2022) DHA Suppresses Hepatic Lipid Accumulation via Cyclin D1 in Zebrafish. Frontiers in nutrition. 8:797510
- Zhang, R., Tu, Y.X., Ye, D., Gu, Z., Chen, Z.X., Sun, Y. (2022) A Germline-Specific Regulator of Mitochondrial Fusion is Required for Maintenance and Differentiation of Germline Stem and Progenitor Cells. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(36):e2203631
- Budine, T.E., de Sena-Tomás, C., Williams, M.L.K., Sepich, D.S., Targoff, K.L., Solnica-Kreze, L. (2020) Gon4l/Udu Regulates Cardiomyocyte Proliferation and Maintenance of Ventricular Chamber Identity During Zebrafish Development. Developmental Biology. 462(2):223-234
- Luo, J., Liu, P., Lu, C., Bian, W., Su, D., Zhu, C., Xie, S., Pan, Y., Li, N., Cui, W., Pei, D.S., Yang, X. (2020) Stepwise crosstalk between aberrant Nf1, Tp53 and Rb signalling pathways induces gliomagenesis in zebrafish. Brain : a journal of neurology. 144(2):615-635
- He, S., Mansour, M.R., Zimmerman, M.W., Ki, D.H., Layden, H.M., Akahane, K., Gjini, E., de Groh, E.D., Perez-Atayde, A.R., Zhu, S., Epstein, J.A., Look, A.T. (2016) Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain. eLIFE. 5
- He, Y., Cai, C., Tang, D., Sun, S., Li, H. (2014) Effect of histone deacetylase inhibitors trichostatin A and valproic acid on hair cell regeneration in zebrafish lateral line neuromasts. Frontiers in Cellular Neuroscience. 8:382
- Sun, D., Zhang, Y., Wang, C., Hua, X., Zhang, X.A., and Yan, J. (2013) Sox9-related signaling controls zebrafish juvenile ovary-testis transformation. Cell Death & Disease. 4:e930
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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