Gene
prodha
- ID
- ZDB-GENE-041008-73
- Name
- proline dehydrogenase (oxidase) 1a
- Symbol
- prodha Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have FAD binding activity and proline dehydrogenase activity. Predicted to be involved in proline catabolic process to glutamate. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in amino acid metabolic disorder; hyperprolinemia type 1; and schizophrenia 4. Orthologous to human PRODH (proline dehydrogenase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7136007 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hyperprolinemia type 1 | Alliance | Hyperprolinemia, type I | 239500 |
| schizophrenia 4 | Alliance | {Schizophrenia, susceptibility to, 4} | 600850 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | FAD-linked oxidoreductase-like | Proline dehydrogenase domain | Proline oxidase family |
|---|---|---|---|---|
|
UniProtKB:A0A8M1RHY4
|
617 | |||
|
UniProtKB:E7FFM5
|
629 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
prodha-201
(1)
|
Ensembl | 1,890 nt | ||
| mRNA |
prodha-203
(1)
|
Ensembl | 981 nt | ||
| ncRNA |
prodha-002
(1)
|
Ensembl | 771 nt |
Interactions and Pathways
No data available
Plasmids
No data available