Gene
taf1b
- ID
- ZDB-GENE-041008-2
- Name
- TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B
- Symbol
- taf1b Nomenclature History
- Previous Names
-
- si:dkey-81b15.4 (1)
- zgc:110402
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly and nucleolar large rRNA transcription by RNA polymerase I. Predicted to act upstream of or within transcription by RNA polymerase I. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I core factor complex and RNA polymerase transcription factor SL1 complex. Human ortholog(s) of this gene implicated in Lynch syndrome and mismatch repair cancer syndrome. Orthologous to human TAF1B (TATA-box binding protein associated factor, RNA polymerase I subunit B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | RNA polymerase I transcription initiation factor TAF1B/Rrn7 | Rrn7/TAF1B, C-terminal cyclin domain | Rrn7/TAF1B, N-terminal cyclin domain | Transcription initiation factor Rrn7, Zinc-finger |
|---|---|---|---|---|---|
|
UniProtKB:F1R3W0
|
576 | ||||
|
UniProtKB:Q4KMI1
|
576 | ||||
|
UniProtKB:A0A8M9P2J7
|
486 |
Interactions and Pathways
No data available
Plasmids
No data available