ZFIN ID: ZDB-GENE-041008-189
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Gene Name: histidine rich calcium binding protein
Gene Symbol: hrc    Nomenclature History

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Previous Names: HRC (1), im:7139860 (1), si:ch211-173d10.1, si:ch211-173d10.3, trpm4b3 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have calcium activated cation channel activity and calcium ion binding activity. Predicted to be involved in several processes, including cardiac conduction; regulation of T cell cytokine production; and vasoconstriction. Predicted to localize to the integral component of membrane. Is expressed in myotome. Orthologous to human HRC (histidine rich calcium binding protein).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000063347 (2)
GENE EXPRESSION
All Expression Data: 5 figures from 2 publications
Directly Submitted Expression Data: 4 figures (3 images) from Thisse et al., 2004 [IMAGE:7139860]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH hrc HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH hrc VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cardiac conduction (more)
Cellular Component integral component of membrane (more)
Molecular Function calcium activated cation channel activity (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR005821 Ion transport domain
Family IPR015666 Sarcoplasmic reticulum histidine-rich calcium-binding protein
Family IPR029581 Transient receptor potential cation channel subfamily M member 4
Domain IPR041491 TRPM, SLOG domain
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA hrc-201 (1)    Ensembl 1753
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si:ch211-173d10.1-201 (1)    Ensembl 1307
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si:ch211-173d10.1-202 (1)    Ensembl 1252
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Browsers: Ensembl,  ZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM hrc No data available
MARKER RELATIONSHIPS
hrc Contained in: [BAC] CH211-173D10 (1)
hrc Encodes: [EST] IMAGE:7139860 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA GenBank:KF305312 (1) 3680 bp
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Genomic GenBank:CU571308 (1) 141745 bp
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Polypeptide UniProtKB:S5TZ97 (1) 1225 aa
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Sequence Information (all 10)
ORTHOLOGY for hrc ( Chr: 12 )
CITATIONS (22)