smpdl3b

ID

ZDB-GENE-041008-132

Name

sphingomyelin phosphodiesterase acid like 3B

Symbol

smpdl3b Nomenclature History

Previous Names

im:7137990 (1)
si:ch1073-55d10.1 (1)

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable phosphoric diester hydrolase activity. Predicted to act upstream of or within sphingomyelin catabolic process. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human SMPDL3B (sphingomyelin phosphodiesterase acid like 3B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7137990 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With smpdl3b Human Ortholog

No data available

Associated With smpdl3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR041805	Acid sphingomyelinase/endopolyphosphatase, metallophosphatase domain
Domain	IPR045473	Sphingomyelin phosphodiesterase, C-terminal domain
Family	IPR017064	Acid sphingomyelinase-like phosphodiesterase, predicted
Homologous_superfamily	IPR029052	Metallo-dependent phosphatase-like