ZFIN is now using GRCz12tu for Genomic Data
Gene
tgm2a
- ID
- ZDB-GENE-040912-78
- Name
- transglutaminase 2, C polypeptide A
- Symbol
- tgm2a Nomenclature History
- Previous Names
-
- TG2c (1)
- tgm2
- zgc:101081
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable protein-glutamine gamma-glutamyltransferase activity. Predicted to be involved in phospholipase C-activating G protein-coupled receptor signaling pathway and positive regulation of apoptotic process. Predicted to act upstream of or within peptide cross-linking and proteolysis. Predicted to be located in several cellular components, including chromosome; cytosol; and extracellular region. Predicted to be active in mitochondrion. Is expressed in muscle; myotome; skeletal muscle; and somite. Orthologous to human TGM2 (transglutaminase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7137767 (2 images)
- IMAGE:7146244 (3 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR013808 | Transglutaminase, active site |
| Domain | IPR001102 | Transglutaminase, N-terminal |
| Domain | IPR002931 | Transglutaminase-like |
| Domain | IPR008958 | Transglutaminase, C-terminal |
| Family | IPR023608 | Protein-glutamine gamma-glutamyltransferase, animal |
| Family | IPR050779 | Protein-glutamine gamma-glutamyltransferases |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014756 | Immunoglobulin E-set |
| Homologous_superfamily | IPR036238 | Transglutaminase, C-terminal domain superfamily |
| Homologous_superfamily | IPR036985 | Transglutaminase-like superfamily |
| Homologous_superfamily | IPR038765 | Papain-like cysteine peptidase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Immunoglobulin E-set | Immunoglobulin-like fold | Papain-like cysteine peptidase superfamily | Protein-glutamine gamma-glutamyltransferase, animal | Protein-glutamine gamma-glutamyltransferases | Transglutaminase, active site | Transglutaminase, C-terminal | Transglutaminase, C-terminal domain superfamily | Transglutaminase-like | Transglutaminase-like superfamily | Transglutaminase, N-terminal |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q66L63 | InterPro | 679 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tgm2a-201
(1)
|
Ensembl | 2,120 nt | ||
| ncRNA |
ottdart00000062056
(1)
|
Ensembl | 976 nt | ||
| ncRNA |
ottdart00000062057
(1)
|
Ensembl | 788 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers