Gene

rtknb

ID

ZDB-GENE-040912-64

Name

rhotekin b

Symbol

rtknb Nomenclature History

Previous Names

rtkn2b
si:dkey-264m23.3
zgc:101635

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to be involved in actomyosin contractile ring assembly; mitotic cytokinesis; and septin ring organization. Predicted to act upstream of or within Rho protein signal transduction and septin cytoskeleton organization. Predicted to be active in actomyosin contractile ring. Is expressed in several structures, including head mesenchyme; lens; otic vesicle; pectoral fin bud; and solid lens vesicle. Orthologous to human RTKN (rhotekin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:101635 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rtknb Human Ortholog

No data available

Associated With rtknb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR011072	HR1 rho-binding domain
Domain	IPR012966	Anillin homology domain
Family	IPR051364	Cytokinesis and Rho signaling-related protein
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR036274	HR1 repeat superfamily