ZFIN is now using GRCz12tu for Genomic Data
Gene
fth1b
- ID
- ZDB-GENE-040912-30
- Name
- ferritin, heavy polypeptide 1b
- Symbol
- fth1b Nomenclature History
- Previous Names
-
- zgc:92245 (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ferric iron binding activity and ferrous iron binding activity. Predicted to act upstream of or within intracellular iron ion homeostasis and iron ion transport. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in hemochromatosis type 5 and neurodegeneration with brain iron accumulation. Orthologous to several human genes including FTH1 (ferritin heavy chain 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hemochromatosis type 5 | Alliance | ?Hemochromatosis, type 5 | 615517 |
| Neurodegeneration with brain iron accumulation 9 | 620669 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Ferritin | Ferritin, conserved site | Ferritin/DPS domain | Ferritin-like | Ferritin-like diiron domain | Ferritin-like superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q66HX7 | InterPro | 177 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers