ZFIN ID: ZDB-GENE-040824-4
Gene Name: hairy-related 11
Gene Symbol: her11    Nomenclature History

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Previous Name: him (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Exhibits protein heterodimerization activity. Involved in midbrain-hindbrain boundary development and negative regulation of neurogenesis. Predicted to localize to the nucleus. Is expressed in several structures, including heart; liver; margin; midbrain hindbrain boundary; and midbrain hindbrain boundary neural plate.
Genome Resources: Alliance (1),  Gene:445409 (1),  Ensembl(GRCz11):ENSDARG00000002707 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa47 Point Mutation Unknown Unknown ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-her11 N/A 2
MO2-her11 N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH her11 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH her11 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process midbrain-hindbrain boundary development (more)
Cellular Component nucleus (more)
Molecular Function protein binding (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Family IPR032644 Transcription factor HES-7
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA her11-201 (1)    Ensembl 1166
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM her11 No data available
MARKER RELATIONSHIPS
her11 Contained in: [BAC] CH73-271E23 (1), CH211-153K16 (1)
her11 Encodes: [cDNA] MGC:193985 (1), MGC:193998 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001003886 (1) 1155 bp
Genomic GenBank:BX323810 166625 bp
Select Tool
Polypeptide UniProtKB:Q6W4T8 (1) 274 aa
Sequence Information (all 17)
ORTHOLOGY for her11 ( Chr: 14 )
CITATIONS (27)