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ZIRC
ZFIN ID: ZDB-GENE-040818-1
Gene Name: signal transducer and activator of transcription 5b
Gene Symbol: stat5b
Sequence Ontology ID : SO:0000704

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Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Predicted to be involved in  ...
GENE EXPRESSION
All Expression Data: 4 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:113865]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 4 (96.0h-120.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb395 Small Deletion Unknown Premature Stop TALEN
ihb396 Small Deletion Unknown Frameshift, Premature Stop TALEN
la027302Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31864 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: Fig. 5 from Huang et al., 2018
    Observed in:
    DISEASE ASSOCIATED WITH stat5b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Leukemia, acute promyelocytic, somatic 102578
    Leukemia, acute promyelocytic, somatic 102578
    Growth hormone insensitivity with immunodeficiency 245590
    Growth hormone insensitivity with immunodeficiency 245590
    Leukemia, acute promyelocytic, somatic 102578
    Growth hormone insensitivity with immunodeficiency 245590
    Leukemia, acute promyelocytic, somatic 102578
    DISEASE ASSOCIATED WITH stat5b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process growth hormone receptor signaling pathway via JAK-STAT (more)
    Cellular Component cytoplasm (more)
    Molecular Function DNA binding (more)
    GO Terms (all 15)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    aberrant processed transcript stat5b-201 (1) 1433
    mRNA stat5b-202 (1) 3525
    stat5b-203 (1) 3528
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM stat5b No data available
    MARKER RELATIONSHIPS
    stat5bContained in: [BAC] DKEYP-45G11 (1)
    stat5bEncodes: [cDNA] MGC:113865 (1) (order this), MGC:162064 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001003984 (1) 3502bp
    Genomic GenBank:CR354395 (1) 160211bp
    Select Tool
    Polypeptide UniProtKB:F1QWX2 (1) 787aa
    Sequence Clusters UniGene:140952 (1)
    Sequence Information (all 19)
    ORTHOLOGY for stat5b (Chr: 12)
    CITATIONS (36)