Gene

ypel1

ID

ZDB-GENE-040808-41

Name

yippee-like 1

Symbol

ypel1 Nomenclature History

Previous Names

zgc:100954

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Is expressed in several structures, including axis; corpuscles of Stannius; mesoderm; nervous system; and neural plate. Orthologous to human YPEL1 (yippee like 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7147101 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Allele	Type	Localization	Consequence	Mutagen	Supplier
sa20357	Allele with one point mutation	Unknown	Splice Site	ENU	Zebrafish International Resource Center (ZIRC) (order this) European Zebrafish Resource Center (EZRC) (order this)

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Sequence Targeting Reagents

No data available

Human Disease

Associated With ypel1 Human Ortholog

No data available

Associated With ypel1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004910	Yippee/Mis18/Cereblon
Domain	IPR034751	Yippee domain
Family	IPR039058	Yippee family

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Domain Details Per Protein

Protein	Additional Resources	Length	Yippee domain	Yippee family	Yippee/Mis18/Cereblon
UniProtKB:Q6AXK6	InterPro	119
UniProtKB:A0AB32TQV7	InterPro	96

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Transcripts

Genome Browsers

Genome Build: GRCz11Chromosome: 5

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	ypel1-201 (1) Ensembl	Ensembl		1,731 nt	Select Tool ZFIN BLAST
mRNA	ypel1-202 (1) Ensembl	Ensembl		595 nt	Select Tool ZFIN BLAST

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Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	DKEY-72G15	BX005237	ZFIN Curated Data
Encodes	EST	IMAGE:7147101	CK684597	Thisse et al., 2004
Encodes	cDNA	MGC:100954	BC079498	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_001003780 (1)	1765 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX005237 (1)	213290 nt	Select Tool MegaBLAST
Polypeptide	UniProtKB:Q6AXK6 (1)	119 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	YPEL1	22	Ensembl:ENSG00000100027 Gene:29799 HGNC:12845 OMIM:608082	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)
Mouse	Ypel1	16	Ensembl:ENSMUSG00000022773 Gene:106369 MGI:1913303	Amino acid sequence comparison (1) Conserved genome location (synteny) (1)

Citations

Include unpublished citations

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

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