Gene
entpd1
- ID
- ZDB-GENE-040801-58
- Name
- ectonucleoside triphosphate diphosphohydrolase 1
- Symbol
- entpd1 Nomenclature History
- Previous Names
-
- NTPDase1 (1)
- zgc:100819
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity and hydrolase activity. Involved in cellular response to methanol; response to copper ion; and response to ethanol. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 64. Is expressed in several structures, including cardiovascular system; digestive system; hindbrain neural plate; nervous system; and periderm. Orthologous to human ENTPD1 (ectonucleoside triphosphate diphosphohydrolase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7151329 (24 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 64 | Alliance | Spastic paraplegia 64, autosomal recessive | 615683 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR000407 | Nucleoside phosphatase GDA1/CD39 |
Domain Details Per Protein
| Protein | Length | Nucleoside phosphatase GDA1/CD39 |
|---|---|---|
|
UniProtKB:E7FG27
|
496 | |
|
UniProtKB:Q6DC46
|
492 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
entpd1-201
(1)
|
Havana | 2420 nt | |
| mRNA |
entpd1-203
(1)
|
Havana | 796 nt |
Interactions and Pathways
No data available
Plasmids
No data available