Gene
bag3
- ID
- ZDB-GENE-040801-40
- Name
- BCL2 associated athanogene 3
- Symbol
- bag3 Nomenclature History
- Previous Names
-
- zgc:100859
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have chaperone binding activity. Involved in heart contraction; locomotory behavior; and skeletal muscle tissue development. Localizes to Z disc. Used to study muscular dystrophy. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1HH and myofibrillar myopathy 6. Is expressed in fast muscle cell; heart; muscle; and slow muscle cell. Orthologous to human BAG3 (BAG cochaperone 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 25 figures from 7 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| dilated cardiomyopathy 1HH | Alliance | Cardiomyopathy, dilated, 1HH | 613881 |
| myofibrillar myopathy 6 | Alliance | Myopathy, myofibrillar, 6 | 612954 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | BAG domain | BAG domain superfamily | Molecular chaperone regulator BAG | WW domain | WW domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6DC38
|
459 |
Interactions and Pathways
No data available
Plasmids
No data available