Gene

chst1

ID

ZDB-GENE-040801-21

Name

carbohydrate (keratan sulfate Gal-6) sulfotransferase 1

Symbol

chst1 Nomenclature History

Previous Names

zgc:100904

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to enable N-acetylglucosamine 6-O-sulfotransferase activity and keratan sulfotransferase activity. Predicted to be involved in N-acetylglucosamine metabolic process and keratan sulfate metabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in Golgi membrane. Is expressed in central nervous system; otic placode; retina; and retinal inner nuclear layer. Orthologous to human CHST1 (carbohydrate sulfotransferase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7143602 (4 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With chst1 Human Ortholog

No data available

Associated With chst1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000863	Sulfotransferase domain
Family	IPR016469	Carbohydrate sulfotransferase
Family	IPR051135	Gal/GlcNAc/GalNAc Sulfotransferase
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase