Gene

dnajb4

ID

ZDB-GENE-040801-192

Name

DnaJ heat shock protein family (Hsp40) member B4

Symbol

dnajb4 Nomenclature History

Previous Names

zgc:91922

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable chaperone binding activity and unfolded protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within protein folding. Predicted to be active in cytosol. Orthologous to human DNAJB4 (DnaJ heat shock protein family (Hsp40) member B4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7147838 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dnajb4 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
congenital myopathy 21	Alliance	Congenital myopathy 21 with early respiratory failure	620326

Associated With dnajb4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018253	DnaJ domain, conserved site
Domain	IPR001623	DnaJ domain
Domain	IPR002939	Chaperone DnaJ, C-terminal
Family	IPR051339	DnaJ homolog subfamily B
Homologous_superfamily	IPR008971	HSP40/DnaJ peptide-binding
Homologous_superfamily	IPR036869	Chaperone J-domain superfamily