Gene
me2
- ID
- ZDB-GENE-040801-147
- Name
- malic enzyme 2, NAD(+)-dependent, mitochondrial
- Symbol
- me2 Nomenclature History
- Previous Names
-
- zgc:100941
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable malate dehydrogenase (decarboxylating) (NADP+) activity. Predicted to be involved in malate metabolic process and pyruvate metabolic process. Predicted to be active in mitochondrion. Is expressed in several structures, including cardiovascular system; hatching gland; musculature system; polster; and visual system. Orthologous to human ME2 (malic enzyme 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7146407 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR015884 | Malic enzyme, conserved site |
| Domain | IPR012301 | Malic enzyme, N-terminal domain |
| Domain | IPR012302 | Malic enzyme, NAD-binding |
| Family | IPR001891 | Malic oxidoreductase |
| Homologous_superfamily | IPR036291 | NAD(P)-binding domain superfamily |
| Homologous_superfamily | IPR037062 | Malic enzyme, N-terminal domain superfamily |
| Homologous_superfamily | IPR046346 | Aminoacid dehydrogenase-like, N-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Aminoacid dehydrogenase-like, N-terminal domain superfamily | Malic enzyme, conserved site | Malic enzyme, NAD-binding | Malic enzyme, N-terminal domain | Malic enzyme, N-terminal domain superfamily | Malic oxidoreductase | NAD(P)-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A5PN55
|
581 |
Interactions and Pathways
No data available
Plasmids
No data available