Gene

ptpa

ID
ZDB-GENE-040801-11
Name
protein phosphatase 2 phosphatase activator
Symbol
ptpa Nomenclature History
Previous Names
  • fc23d07
  • ppp2r4 (1)
  • wu:fc23d07
  • zgc:92766
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have peptidyl-prolyl cis-trans isomerase activity and protein tyrosine phosphatase activator activity. Predicted to be involved in mitotic spindle organization. Predicted to localize to cytoplasm; nucleus; and protein phosphatase type 2A complex. Orthologous to human PTPA (protein phosphatase 2 phosphatase activator).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ptpa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Parkinson's disease 25 Alliance Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development 620482
Associated With ptpa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004327 Phosphotyrosyl phosphatase activator, PTPA
Homologous_superfamily IPR037218 PTPA superfamily
Homologous_superfamily IPR043170 Phosphotyrosyl phosphatase activator, C-terminal lid domain
Domain Details Per Protein
Protein Length Phosphotyrosyl phosphatase activator, C-terminal lid domain Phosphotyrosyl phosphatase activator, PTPA PTPA superfamily
UniProtKB:A2CF49 324
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ptpa-201 (1) Ensembl 558 nt
mRNA ptpa-202 (1) Ensembl 1,991 nt
mRNA ptpa-203 (1) Ensembl 6,264 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations