Gene

si:dkey-192d15.2

ID

ZDB-GENE-040724-74

Name

si:dkey-192d15.2

Symbol

si:dkey-192d15.2 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have ATP binding activity; lipid binding activity; and protein kinase activity. Predicted to be involved in lipid transport; lipoprotein metabolic process; and protein phosphorylation. Predicted to localize to extracellular region and integral component of membrane. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis and schizophrenia. Orthologous to several human genes including APOL1 (apolipoprotein L1); APOL2 (apolipoprotein L2); and APOL3 (apolipoprotein L3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With si:dkey-192d15.2 Human Ortholog

No data available

Associated With si:dkey-192d15.2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Family	IPR008405	Apolipoprotein L
Family	IPR051131	NEK Ser/Thr protein kinase family, NIMA subfamily
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily