ZFIN is now using GRCz12tu for Genomic Data
Gene
fbxo22
- ID
- ZDB-GENE-040724-68
- Name
- F-box protein 22
- Symbol
- fbxo22 Nomenclature History
- Previous Names
-
- si:busm1-132m23.3
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Unknown
- Description
- Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and regulation of skeletal muscle fiber development. Predicted to be part of SCF ubiquitin ligase complex. Human ortholog(s) of this gene implicated in disease of mental health. Orthologous to human FBXO22 (F-box protein 22).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Tayoun-Maawali syndrome | Alliance | Tayoun-Maawali syndrome | 621184 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | F-box domain | F-box-like domain superfamily | FIST, C-domain |
|---|---|---|---|---|---|
| UniProtKB:A0A8M9QC10 | InterPro | 208 | |||
| UniProtKB:Q5SPK4 | InterPro | 385 | |||
| UniProtKB:A0AC58FZD9 | InterPro | 208 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA | fbxo22-001 (1) | Havana | 1,681 nt | ||
| mRNA |
fbxo22-201
(1)
|
Ensembl | 3,263 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers