ZFIN is now using GRCz12tu for Genomic Data
Gene
polq
- ID
- ZDB-GENE-040724-232
- Name
- polymerase (DNA directed), theta
- Symbol
- polq Nomenclature History
- Previous Names
-
- si:rp71-1p14.5 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-directed DNA polymerase activity. Predicted to be involved in double-strand break repair via alternative nonhomologous end joining. Predicted to act upstream of or within DNA-templated DNA replication. Predicted to be located in nucleus. Is expressed in oocyte and testis. Orthologous to human POLQ (DNA polymerase theta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Takata et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019760 | DNA-directed DNA polymerase, family A, conserved site |
| Domain | IPR001098 | DNA-directed DNA polymerase, family A, palm domain |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR011545 | DEAD/DEAH box helicase domain |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR046931 | DNA polymerase theta-like, helix-turn-helix domain |
| Domain | IPR048960 | POLQ-like, helical domain |
| Family | IPR002298 | DNA polymerase A |
| Homologous_superfamily | IPR012337 | Ribonuclease H-like superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036397 | Ribonuclease H superfamily |
| Homologous_superfamily | IPR043502 | DNA/RNA polymerase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | DEAD/DEAH box helicase domain | DNA-directed DNA polymerase, family A, conserved site | DNA-directed DNA polymerase, family A, palm domain | DNA polymerase A | DNA polymerase theta-like, helix-turn-helix domain | DNA/RNA polymerase superfamily | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase | POLQ-like, helical domain | Ribonuclease H-like superfamily | Ribonuclease H superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1Q4P4 | InterPro | 2576 | ||||||||||||
| UniProtKB:A0A8M9Q371 | InterPro | 2579 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers