Gene
mpc1
- ID
- ZDB-GENE-040718-94
- Name
- mitochondrial pyruvate carrier 1
- Symbol
- mpc1 Nomenclature History
- Previous Names
-
- zgc:92707
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable pyruvate transmembrane transporter activity. Involved in pyruvate metabolic process. Acts upstream of with a positive effect on digestive tract development. Predicted to be located in membrane and mitochondrion. Predicted to be active in mitochondrial inner membrane. Is expressed in several structures, including digestive system; female organism; head; pectoral fin; and vasculature. Human ortholog(s) of this gene implicated in mitochondrial pyruvate carrier deficiency. Orthologous to human MPC1 (mitochondrial pyruvate carrier 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92707 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Sandoval et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial pyruvate carrier deficiency | Alliance | Mitochondrial pyruvate carrier deficiency | 614741 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR005336 | Mitochondrial pyruvate carrier |
Domain Details Per Protein
| Protein | Length | Mitochondrial pyruvate carrier |
|---|---|---|
|
UniProtKB:F1Q6Z3
|
109 |
Interactions and Pathways
No data available
Plasmids
No data available