Gene

cacnb1

ID

ZDB-GENE-040718-399

Name

calcium channel, voltage-dependent, beta 1 subunit

Symbol

cacnb1 Nomenclature History

Previous Names

dihydropyridine receptor b1 (1)
red
relaxed
zgc:91982

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Contributes to voltage-gated calcium channel activity. Involved in muscle contraction and voltage-gated calcium channel complex assembly. Localizes to voltage-gated calcium channel complex. Is expressed in several structures, including basal plate midbrain region; hatching gland; musculature system; nervous system; and polster. Orthologous to human CACNB1 (calcium voltage-gated channel auxiliary subunit beta 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:91982 (22 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 9 figures from 5 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cacnb1 Human Ortholog

No data available

Associated With cacnb1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001452	SH3 domain
Domain	IPR008145	Guanylate kinase/L-type calcium channel beta subunit
Family	IPR000584	Voltage-dependent calcium channel, L-type, beta subunit
Family	IPR005443	Voltage-dependent calcium channel, L-type, beta-1 subunit
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036028	SH3-like domain superfamily

Domain Details Per Protein

Protein	Length	Guanylate kinase/L-type calcium channel beta subunit	P-loop containing nucleoside triphosphate hydrolase	SH3 domain	SH3-like domain superfamily	Voltage-dependent calcium channel, L-type, beta-1 subunit	Voltage-dependent calcium channel, L-type, beta subunit
UniProtKB:F1R605 InterPro	520
UniProtKB:Q6DG31 InterPro	478
UniProtKB:Q2Q552 InterPro	517
UniProtKB:Q2Q551 InterPro	603
UniProtKB:Q4KPD0 InterPro	520

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
mRNA	cacnb1-202 (1) Ensembl	2043 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	cacnb1-203 (1) Ensembl	1670 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	cacnb1-205 (1) Ensembl	1554 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	cacnb1-004 (1) Ensembl	690 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations