Gene

naxe

ID
ZDB-GENE-040718-362
Name
NAD(P)HX epimerase
Symbol
naxe Nomenclature History
Previous Names
  • aibp1 (1)
  • apoa1bp (1)
  • zgc:92263
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable NAD(P)HX epimerase activity. Predicted to act upstream of or within lipid transport. Predicted to be located in extracellular region. Predicted to be active in mitochondrion. Orthologous to human NAXE (NAD(P)HX epimerase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Kim et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
lux7Allele with one insertionExon 4UnknownCRISPR
lux8Allele with one deletionExon 5UnknownCRISPR
muz108Allele with one point mutationUnknownPremature StopENU
1 - 3 of 3
Show
Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-naxeN/AFang et al., 2013
1 - 1 of 1
Show
Human Disease
Associated With naxe Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy 617186
1 - 1 of 1
Associated With naxe Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004443 YjeF N-terminal domain
Family IPR032976 YjeF N-terminal domain-containing protein NAXE-like
Homologous_superfamily IPR036652 YjeF N-terminal domain superfamily
1 - 3 of 3
Domain Details Per Protein
Protein Additional Resources Length YjeF N-terminal domain YjeF N-terminal domain-containing protein NAXE-like YjeF N-terminal domain superfamily
UniProtKB:Q6DHK1 InterPro 283
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 19
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA naxe-201 (1) Ensembl 1,307 nt
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Construct Regulatory Region Coding Sequence Species Tg Lines Citations
Tg(hsp70l:naxe-2A-mRFP)
  • Danio rerio
1Schneider et al., 2018
1 - 1 of 1
Show
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-312O15ZFIN Curated Data
Contained inBACDKEYP-84F11ZFIN Curated Data
EncodescDNAMGC:92263ZFIN Curated Data
1 - 3 of 3
Show
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanNAXE1
Conserved genome location (synteny) (1)
Amino acid sequence comparison (2)
MouseNaxe3
Conserved genome location (synteny) (1)
Amino acid sequence comparison (2)
Citations
1 - 8 of 8
Show