Gene
vamp1b
- ID
- ZDB-GENE-040718-265
- Name
- vesicle associated membrane protein 1b
- Symbol
- vamp1b Nomenclature History
- Previous Names
-
- zgc:92912
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have SNAP receptor activity and syntaxin-1 binding activity. Predicted to be involved in SNARE complex assembly. Predicted to localize to SNARE complex and plasma membrane. Is expressed in hindbrain; midbrain; neurons; retina; and spinal cord. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome and spastic ataxia 1. Orthologous to human VAMP1 (vesicle associated membrane protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92912 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spastic ataxia 1 | Alliance | Spastic ataxia 1, autosomal dominant | 108600 |
| Myasthenic syndrome, congenital, 25 | 618323 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Synaptobrevin-like | Synaptobrevin/Vesicle-associated membrane protein | v-SNARE, coiled-coil homology domain |
|---|---|---|---|---|
|
UniProtKB:Q6DGI1
|
118 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zgc:92912-201
(1)
|
Ensembl | 1,060 nt |
Interactions and Pathways
No data available
Plasmids
No data available