Gene
vamp1b
- ID
- ZDB-GENE-040718-265
- Name
- vesicle associated membrane protein 1b
- Symbol
- vamp1b Nomenclature History
- Previous Names
-
- zgc:92912
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have SNAP receptor activity and syntaxin binding activity. Predicted to be involved in SNARE complex assembly. Predicted to localize to SNARE complex and plasma membrane. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome and spastic ataxia 1. Is expressed in hindbrain; midbrain; neurons; retina; and spinal cord. Orthologous to human VAMP1 (vesicle associated membrane protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92912 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spastic ataxia 1 | Alliance | Spastic ataxia 1, autosomal dominant | 108600 |
| Myasthenic syndrome, congenital, 25 | 618323 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Synaptobrevin-like | Synaptobrevin/Vesicle-associated membrane protein | v-SNARE, coiled-coil homology domain |
|---|---|---|---|---|
|
UniProtKB:Q6DGI1
|
118 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zgc:92912-201
(1)
|
Ensembl | 1,060 nt |
Interactions and Pathways
No data available
Plasmids
No data available