Gene

rab40b

ID

ZDB-GENE-040718-257

Name

RAB40B, member RAS oncogene family

Symbol

rab40b Nomenclature History

Previous Names

zgc:92926

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have GTPase activity. Predicted to be involved in Rab protein signal transduction; intracellular protein transport; and protein localization to plasma membrane. Predicted to localize to endosome; plasma membrane; and synaptic vesicle. Human ortholog(s) of this gene implicated in deafness-intellectual disability, Martin-Probst type syndrome. Is expressed in olfactory placode. Orthologous to human RAB40AL (RAB40A like); RAB40A (RAB40A, member RAS oncogene family); and RAB40B (RAB40B, member RAS oncogene family).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:92926 (7 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rab40b Human Ortholog

No data available

Associated With rab40b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001496	SOCS box domain
Domain	IPR005225	Small GTP-binding domain
Family	IPR001806	Small GTPase
Family	IPR050305	Small GTPase superfamily, Rab
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036036	SOCS box-like domain superfamily