Gene

cdk5r1b

ID
ZDB-GENE-040718-220
Name
cyclin dependent kinase 5, regulatory subunit 1b (p35)
Symbol
cdk5r1b Nomenclature History
Previous Names
  • cdk5r1 (1)
  • p35 (1)
  • zgc:92814 (1)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have cyclin-dependent protein serine/threonine kinase activator activity and kinase activity. Involved in amacrine cell differentiation; embryonic retina morphogenesis in camera-type eye; and retina layer formation. Predicted to localize to plasma membrane and protein kinase 5 complex. Is expressed in basal plate midbrain region and nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdk5r1b Human Ortholog
No data available
Associated With cdk5r1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004944 Cyclin-dependent kinase 5 activator
Homologous_superfamily IPR036915 Cyclin-like superfamily
Domain Details Per Protein
Protein Length Cyclin-dependent kinase 5 activator Cyclin-like superfamily
UniProtKB:F1Q6W4 304
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cdk5r1b-201 (1) Ensembl 1,385 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations