hemk2

ID

ZDB-GENE-040718-206

Name

HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine

Symbol

hemk2 Nomenclature History

Previous Names

n6amt1 (1)
zgc:92834 (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable S-adenosylmethionine-dependent methyltransferase activity and protein methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in nucleus. Predicted to be part of eRF1 methyltransferase complex. Orthologous to human HEMK2 (HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:92834 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hemk2 Human Ortholog

No data available

Associated With hemk2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR002052	DNA methylase, N-6 adenine-specific, conserved site
Domain	IPR007848	Methyltransferase small domain
Family	IPR004557	Eukaryotic/archaeal PrmC-related
Family	IPR052190	Eukaryotic/Archaeal PrmC-Related Methyltransferase
Homologous_superfamily	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily