Gene

opn1lw2

ID

ZDB-GENE-040718-141

Name

opsin 1 (cone pigments), long-wave-sensitive, 2

Symbol

opn1lw2 Nomenclature History

Previous Names

zgc:92632 (1)

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to enable G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to act upstream of or within signal transduction and visual perception. Predicted to be located in membrane. Predicted to be active in photoreceptor outer segment and plasma membrane. Is expressed in several structures, including endocrine system; heart; liver; red sensitive photoreceptor cell; and visual system. Human ortholog(s) of this gene implicated in blue cone monochromacy; red color blindness; and red-green color blindness. Orthologous to several human genes including OPN1LW (opsin 1, long wave sensitive).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

24 figures from 20 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With opn1lw2 Human Ortholog

No data available

Associated With opn1lw2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR027430	Visual pigments (opsins) retinal binding site
Domain	IPR017452	GPCR, rhodopsin-like, 7TM
Family	IPR000276	G protein-coupled receptor, rhodopsin-like
Family	IPR000378	Opsin red/green sensitive
Family	IPR001760	Opsin
Family	IPR050125	G-protein coupled receptor opsins

Domain Details Per Protein

Protein	Length	GPCR, rhodopsin-like, 7TM	G-protein coupled receptor opsins	G protein-coupled receptor, rhodopsin-like	Opsin	Opsin red/green sensitive	Visual pigments (opsins) retinal binding site
UniProtKB:Q8AYN0 InterPro	356

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	opn1lw2-201 (1) Ensembl	Ensembl	1,642 nt	Select Tool ZFIN BLAST
ncRNA	opn1lw2-002 (1) Ensembl	Ensembl	817 nt	Select Tool ZFIN BLAST
ncRNA	opn1lw2-003 (1) Ensembl	Ensembl	862 nt	Select Tool ZFIN BLAST
ncRNA	opn1lw2-004 (1) Ensembl	Ensembl	934 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations