Gene
nubpl
- ID
- ZDB-GENE-040718-140
- Name
- nucleotide binding protein-like
- Symbol
- nubpl Nomenclature History
- Previous Names
-
- zgc:92633 (1)
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have 4 iron, 4 sulfur cluster binding activity. Predicted to be involved in iron-sulfur cluster assembly and mitochondrial respiratory chain complex I assembly. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex I deficiency. Orthologous to human NUBPL (nucleotide binding protein like).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6897069 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
nuclear type mitochondrial complex I deficiency 21 | Alliance | Mitochondrial complex I deficiency, nuclear type 21 | 618242 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR000808 | Iron-sulfur cluster carrier protein-like, conserved site |
Family | IPR019591 | Mrp/NBP35 ATP-binding protein |
Family | IPR033756 | Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 |
Family | IPR044304 | Iron-sulfur protein NUBPL-like |
Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
Protein | Length | Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 | Iron-sulfur cluster carrier protein-like, conserved site | Iron-sulfur protein NUBPL-like | Mrp/NBP35 ATP-binding protein | P-loop containing nucleoside triphosphate hydrolase |
---|---|---|---|---|---|---|
UniProtKB:Q6DH61
|
327 |
Interactions and Pathways
No data available
Plasmids
No data available