Gene

otub1a

ID
ZDB-GENE-040718-108
Name
OTU deubiquitinase, ubiquitin aldehyde binding 1a
Symbol
otub1a Nomenclature History
Previous Names
  • otub1l
  • fb17f04 (1)
  • wu:fb17f04 (1)
  • zgc:92685
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have NEDD8-specific protease activity; thiol-dependent ubiquitin-specific protease activity; and ubiquitin binding activity. Predicted to be involved in protein K48-linked deubiquitination. Predicted to localize to nucleus. Orthologous to human OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Tse et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With otub1a Human Ortholog
No data available
Associated With otub1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003323 OTU domain
Family IPR016615 Ubiquitin thioesterase Otubain
Family IPR019400 Peptidase C65, otubain
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Homologous_superfamily IPR042467 Peptidase C65, otubain, subdomain 2
Homologous_superfamily IPR042468 Peptidase C65, otubain, subdomain 1
Domain Details Per Protein
Protein Length OTU domain Papain-like cysteine peptidase superfamily Peptidase C65, otubain Peptidase C65, otubain, subdomain 1 Peptidase C65, otubain, subdomain 2 Ubiquitin thioesterase Otubain
UniProtKB:Q6DH16 267
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations