ZFIN is now using GRCz12tu for Genomic Data
Gene
ltv1
- ID
- ZDB-GENE-040712-1
- Name
- LTV1 ribosome biogenesis factor
- Symbol
- ltv1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Involved in ribosome biogenesis. Acts upstream of or within several processes, including cartilage morphogenesis; definitive hemopoiesis; and rRNA processing. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including digestive system; eye; immature eye; midbrain; and segmental plate. Human ortholog(s) of this gene implicated in inflammatory poikiloderma with hair abnormalities and acral keratoses. Orthologous to human LTV1 (LTV1 ribosome biogenesis factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103432 (20 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| inflammatory poikiloderma with hair abnormalities and acral keratoses | Alliance | Inflammatory poikiloderma with hair abnormalities and acral keratoses | 620199 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR007307 | Low temperature viability protein Ltv1 |
Domain Details Per Protein
| Protein | Additional Resources | Length | Low temperature viability protein Ltv1 |
|---|---|---|---|
| UniProtKB:F1R9T9 | InterPro | 473 | |
| UniProtKB:Q5U3J8 | InterPro | 469 | |
| UniProtKB:A0A8M9PP26 | InterPro | 472 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers