ZFIN is now using GRCz12tu for Genomic Data
Gene
pnp4a
- ID
- ZDB-GENE-040625-83
- Name
- purine nucleoside phosphorylase 4a
- Symbol
- pnp4a Nomenclature History
- Previous Names
-
- zgc:86889 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable purine-nucleoside phosphorylase activity. Predicted to act upstream of or within purine ribonucleoside salvage. Predicted to be active in cytoplasm. Is expressed in several structures, including eye; integument; iridoblast; neural crest; and optic vesicle.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 21 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6904627 (22 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Deis et al., 2024
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018099 | Purine phosphorylase, family 2, conserved site |
| Domain | IPR000845 | Nucleoside phosphorylase domain |
| Family | IPR011268 | Purine nucleoside phosphorylase |
| Family | IPR011270 | Purine nucleoside phosphorylase I, inosine/guanosine-specific |
| Family | IPR029236 | Protein of unknown function DUF4618 |
| Homologous_superfamily | IPR035994 | Nucleoside phosphorylase superfamily |
Domain Details Per Protein
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers