Gene
pnp4a
- ID
- ZDB-GENE-040625-83
- Name
- purine nucleoside phosphorylase 4a
- Symbol
- pnp4a Nomenclature History
- Previous Names
-
- zgc:86889 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable purine-nucleoside phosphorylase activity. Predicted to act upstream of or within purine ribonucleoside salvage. Predicted to be active in cytoplasm. Is expressed in several structures, including eye; integument; iridoblast; neural crest; and optic vesicle.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 20 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6904627 (22 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018099 | Purine phosphorylase, family 2, conserved site |
| Domain | IPR000845 | Nucleoside phosphorylase domain |
| Family | IPR011268 | Purine nucleoside phosphorylase |
| Family | IPR011270 | Purine nucleoside phosphorylase I, inosine/guanosine-specific |
| Homologous_superfamily | IPR035994 | Nucleoside phosphorylase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Nucleoside phosphorylase domain | Nucleoside phosphorylase superfamily | Purine nucleoside phosphorylase | Purine nucleoside phosphorylase I, inosine/guanosine-specific | Purine phosphorylase, family 2, conserved site |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q7SZW5 | InterPro | 291 |
Interactions and Pathways
No data available
Plasmids
No data available
| Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
|---|---|---|---|---|---|
| Tg(pnp4a:NLS-Eos) |
|
| 1 | Gur et al., 2020 | |
| Tg(pnp4a:PALM-mCherry) |
|
| 1 | (5) |
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| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-76P14 | ||
| Encodes | EST | IMAGE:6904627 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:86889 | ZFIN Curated Data |
1 - 3 of 3
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001002102 (1) | 1797 nt | ||
| Genomic | GenBank:AL831791 (1) | 170525 nt | ||
| Polypeptide | UniProtKB:Q7SZW5 (1) | 291 aa |
No data available