Gene
calua
- ID
- ZDB-GENE-040625-166
- Name
- calumenin a
- Symbol
- calua Nomenclature History
- Previous Names
-
- calu
- wu:fd50c05
- zgc:86677 (1)
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable calcium ion binding activity. Predicted to be located in Golgi apparatus; endoplasmic reticulum membrane; and extracellular region. Predicted to be active in endoplasmic reticulum. Is expressed in chordo neural hinge; floor plate; hypochord; notochord; and skeletal system. Orthologous to human CALU (calumenin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7138626 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la024418Tg | Transgenic insertion | Unknown | Unknown | DNA |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair |
|---|---|---|---|---|---|
| UniProtKB:Q6IQP3 | InterPro | 315 | |||
| UniProtKB:Z4YIA7 | InterPro | 317 |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-266A5 | ZFIN Curated Data | |
| Encodes | EST | fd50c05 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:7138626 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:86677 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001002151 (1) | 2051 nt | ||
| Genomic | GenBank:BX465210 (1) | 171708 nt | ||
| Polypeptide | UniProtKB:Z4YIA7 (1) | 317 aa |
- Yan, Y., He, F., Li, Z., Xu, R., Li, T., Su, J., Liu, X., Zhao, M., Wu, W. (2018) The important role of apolipoprotein A-II in ezetimibe driven reduction of high cholesterol diet-induced atherosclerosis. Atherosclerosis. 280:99-108
- Abascal, F., Tress, M., Valencia, A. (2015) The evolutionary fate of alternatively spliced homologous exons after gene duplication. Genome biology and evolution. 7(6):1392-403
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Fernández, I., Vijayakumar, P., Marques, C., Cancela, M.L., Gavaia, P.J., Laizé, V. (2015) Zebrafish vitamin K epoxide reductases: expression in vivo, along extracellular matrix mineralization and under phylloquinone and warfarin in vitro exposure. Fish physiology and biochemistry. 41(3):745-59
- Gao, X., Metzger, U., Panza, P., Mahalwar, P., Alsheimer, S., Geiger, H., Maischein, H.M., Levesque, M.P., Templin, M., Söllner, C. (2015) A Floor-Plate Extracellular Protein-Protein Interaction Screen Identifies Draxin as a Secreted Netrin-1 Antagonist. Cell Reports. 12(4):694-708
- Haug, M.F., Gesemann, M., Lazovic, V., Neuhauss, S.C. (2015) Eumetazoan Cryptochrome Phylogeny and Evolution. Genome biology and evolution. 7(2):601-19
- Kessels, M.Y., Huitema, L.F., Boeren, S., Kranenbarg, S., Schulte-Merker, S., van Leeuwen, J.L., de Vries, S.C. (2014) Proteomics analysis of the zebrafish skeletal extracellular matrix. PLoS One. 9:e90568
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
- Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
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