Gene
fgf17
- ID
- ZDB-GENE-040621-1
- Name
- fibroblast growth factor 17
- Symbol
- fgf17 Nomenclature History
- Previous Names
-
- fgf17b
- zgc:101759
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have growth factor activity; type 1 fibroblast growth factor receptor binding activity; and type 2 fibroblast growth factor receptor binding activity. Involved in several processes, including anterior/posterior pattern specification; mesoderm development; and negative regulation of endodermal cell fate specification. Predicted to localize to cytoplasm and extracellular space. Is expressed in several structures, including blastomere; cardiovascular system; forebrain; paraxial mesoderm; and sensory system. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 20 with or without anosmia. Orthologous to human FGF17 (fibroblast growth factor 17).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7139635 (100 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypogonadotropic hypogonadism 20 with or without anosmia | Alliance | Hypogonadotropic hypogonadism 20 with or without anosmia | 615270 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytokine IL1/FGF | Fibroblast growth factor family |
|---|---|---|---|
|
UniProtKB:A0A8M2BJU5
|
203 | ||
|
UniProtKB:B2GR83
|
215 | ||
|
UniProtKB:Q6SJP8
|
215 |
Interactions and Pathways
Plasmids
No data available