Gene

fgf17

ID
ZDB-GENE-040621-1
Name
fibroblast growth factor 17
Symbol
fgf17 Nomenclature History
Previous Names
  • fgf17b
  • zgc:101759
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have growth factor activity; type 1 fibroblast growth factor receptor binding activity; and type 2 fibroblast growth factor receptor binding activity. Involved in several processes, including anterior/posterior pattern specification; mesoderm development; and negative regulation of endodermal cell fate specification. Predicted to localize to cytoplasm and extracellular space. Is expressed in several structures, including blastomere; cardiovascular system; forebrain; paraxial mesoderm; and sensory system. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 20 with or without anosmia. Orthologous to human FGF17 (fibroblast growth factor 17).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
22 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fgf17 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hypogonadotropic hypogonadism 20 with or without anosmia Alliance Hypogonadotropic hypogonadism 20 with or without anosmia 615270
Associated With fgf17 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002209 Fibroblast growth factor family
Family IPR028287 Fibroblast growth factor 17
Homologous_superfamily IPR008996 Cytokine IL1/FGF
Domain Details Per Protein
Protein Length Cytokine IL1/FGF Fibroblast growth factor 17 Fibroblast growth factor family
UniProtKB:Q6SJP8 215
UniProtKB:A0A0R4IW67 155
UniProtKB:B2GR83 215
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations