Gene

rhoua

ID

ZDB-GENE-040618-3

Name

ras homolog family member Ua

Symbol

rhoua Nomenclature History

Previous Names

rhou
wrch1 (1)
zgc:101642

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Acts upstream of or within atrioventricular canal development and regulation of cell adhesion. Predicted to be active in plasma membrane. Is expressed in several structures, including cardiovascular system; central nervous system; liver; neural tube; and solid lens vesicle. Orthologous to human RHOU (ras homolog family member U).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:101642 (19 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Dickover et al., 2014
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rhoua Human Ortholog

No data available

Associated With rhoua Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR005225	Small GTP-binding domain
Family	IPR001806	Small GTPase
Family	IPR003578	Small GTPase Rho
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase