Gene
nrp2a
- ID
- ZDB-GENE-040611-2
- Name
- neuropilin 2a
- Symbol
- nrp2a Nomenclature History
- Previous Names
-
- npn-2A (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Exhibits identical protein binding activity. Involved in neural crest cell migration; regulation of vascular endothelial growth factor receptor signaling pathway; and vasculogenesis. Predicted to localize to integral component of membrane. Is expressed in axial vasculature; cranial neural crest cell; fin bud; and nervous system. Orthologous to human NRP2 (neuropilin 2).
- Genome Resources
- Note
- None
- All Expression Data
- 15 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- No data available
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Hermans et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000421 | Coagulation factor 5/8 C-terminal domain |
| Domain | IPR000859 | CUB domain |
| Domain | IPR000998 | MAM domain |
| Domain | IPR022579 | Neuropilin, C-terminal |
| Family | IPR014648 | Neuropilin |
| Family | IPR027143 | Neuropilin-2 |
| Homologous_superfamily | IPR008979 | Galactose-binding-like domain superfamily |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR035914 | Spermadhesin, CUB domain superfamily |
Domain Details Per Protein
| Protein | Length | Coagulation factor 5/8 C-terminal domain | Concanavalin A-like lectin/glucanase domain superfamily | CUB domain | Galactose-binding-like domain superfamily | MAM domain | Neuropilin | Neuropilin-2 | Neuropilin, C-terminal | Spermadhesin, CUB domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QN93
|
927 | |||||||||
|
UniProtKB:Q6T495
|
309 | |||||||||
|
UniProtKB:Q69DB6
|
927 | |||||||||
|
UniProtKB:Q6T490
|
927 | |||||||||
|
UniProtKB:Q6T494
|
84 | |||||||||
|
UniProtKB:Q6T868
|
927 | |||||||||
|
UniProtKB:B3DFP6
|
927 | |||||||||
|
UniProtKB:A0A0R4IL03
|
84 |
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl