Gene

nrp1b

ID

ZDB-GENE-040611-1

Name

neuropilin 1b

Symbol

nrp1b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have growth factor binding activity; metal ion binding activity; and transmembrane signaling receptor activity. Involved in several processes, including axon guidance; regulation of vascular endothelial growth factor receptor signaling pathway; and vasculature development. Predicted to localize to integral component of membrane. Is expressed in cranial neural crest cell; mid cerebral vein; retinal ganglion cell layer; somite; and trunk vasculature. Orthologous to human NRP1 (neuropilin 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

15 figures from 12 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nrp1b Human Ortholog

No data available

Associated With nrp1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000421	Coagulation factor 5/8, C-terminal domain
Domain	IPR000859	CUB domain
Domain	IPR000998	MAM domain
Domain	IPR022579	Neuropilin, C-terminal
Family	IPR014648	Neuropilin
Family	IPR050633	Neuropilin/Multicopper Oxidase/Coagulation Factor
Homologous_superfamily	IPR008979	Galactose-binding-like domain superfamily
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily	IPR035914	Spermadhesin, CUB domain superfamily