Gene

dzip1

ID

ZDB-GENE-040526-1

Name

DAZ interacting zinc finger protein 1

Symbol

dzip1 Nomenclature History

Previous Names

igu
iguana
si:dz52i16.1

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have metal ion binding activity and nucleic acid binding activity. Involved in several processes, including circulatory system development; nervous system development; and regulation of signal transduction. Localizes to several cellular components, including ciliary basal body; non-motile cilium; and nucleus. Orthologous to human DZIP1 (DAZ interacting zinc finger protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu116 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 31 figures from 15 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dzip1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
mitral valve prolapse	Alliance	?Mitral valve prolapse 3	610840
spermatogenic failure 47	Alliance	Spermatogenic failure 47	619102

Associated With dzip1 Via Experimental Models

Human Disease	Fish	Conditions	Citations
coloboma	dzip1^{ts294e/ts294e}	standard conditions	Nandamuri et al., 2022

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR013087	Zinc finger C2H2-type
Domain	IPR032714	Cilium assembly protein DZIP1, N-terminal
Family	IPR051241	DZIP and RILPL

Domain Details Per Protein

Protein	Length	Cilium assembly protein DZIP1, N-terminal	DZIP and RILPL	Zinc finger C2H2-type
UniProtKB:F1QNW2 InterPro	897
UniProtKB:F1QHQ9 InterPro	877
UniProtKB:A0A8M2BCZ0 InterPro	887
UniProtKB:Q7T019 InterPro	898
UniProtKB:A0A8M2BD71 InterPro	907
UniProtKB:A0A8M3AT21 InterPro	860

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	dzip1-201 (1) Ensembl	Ensembl	3,260 nt	Select Tool
mRNA	dzip1-202 (1) Ensembl	Ensembl	3,265 nt	Select Tool ZFIN BLAST
mRNA	dzip1-203 (1) Ensembl	Ensembl	3,325 nt	Select Tool ZFIN BLAST
mRNA	dzip1-204 (1) Ensembl	Ensembl	3,200 nt	Select Tool
mRNA	dzip1-205 (1) Ensembl	Ensembl	2,813 nt	Select Tool ZFIN BLAST
mRNA	ottdart00000003879 (1)	Havana	1,612 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations