Gene

abcb10

ID

ZDB-GENE-040525-2

Name

ATP-binding cassette, sub-family B (MDR/TAP), member 10

Symbol

abcb10 Nomenclature History

Previous Names

si:dkey-162b3.3

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Enables ATP hydrolysis activity. Involved in positive regulation of heme biosynthetic process. Acts upstream of or within erythrocyte differentiation. Predicted to be located in membrane. Predicted to be active in mitochondrial inner membrane. Is expressed in kidney. Orthologous to human ABCB10 (ATP binding cassette subfamily B member 10).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Seguin et al., 2017
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With abcb10 Human Ortholog

No data available

Associated With abcb10 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017871	ABC transporter-like, conserved site
Domain	IPR003439	ABC transporter-like, ATP-binding domain
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR011527	ABC transporter type 1, transmembrane domain
Family	IPR039421	Type 1 protein exporter
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036640	ABC transporter type 1, transmembrane domain superfamily

Domain Details Per Protein

Protein	Length	AAA+ ATPase domain	ABC transporter-like, ATP-binding domain	ABC transporter-like, conserved site	ABC transporter type 1, transmembrane domain	ABC transporter type 1, transmembrane domain superfamily	P-loop containing nucleoside triphosphate hydrolase	Type 1 protein exporter
UniProtKB:F1Q5K6 InterPro	710

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	abcb10-201 (1) Ensembl	Ensembl		3,786 nt	Select Tool ZFIN BLAST
mRNA	abcb10-202 (1) Ensembl	Ensembl		2,454 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations