ighd

ID

ZDB-GENE-040513-9

Name

immunoglobulin heavy constant delta

Symbol

ighd Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Unknown

Description

Acts upstream of or within response to lipopolysaccharide. Is expressed in kidney. Human ortholog(s) of this gene implicated in agammaglobulinemia 1 and allergic rhinitis. Orthologous to several human genes including IGHA2 (immunoglobulin heavy constant alpha 2 (A2m marker)); IGHE (immunoglobulin heavy constant epsilon); and IGHG3 (immunoglobulin heavy constant gamma 3 (G3m marker)).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 5 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ighd Human Ortholog

No data available

Associated With ighd Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR003006	Immunoglobulin/major histocompatibility complex, conserved site
Domain	IPR003597	Immunoglobulin C1-set
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013106	Immunoglobulin V-set domain
Family	IPR050380	Immune Recognition and Response Modulators
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily