Gene
ight
- ID
- ZDB-GENE-040513-8
- Name
- immunoglobulin heavy constant tau
- Symbol
- ight Nomenclature History
- Previous Names
-
- ighz (1)
- igz
- ighm2
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Acts upstream of or within response to lipopolysaccharide. Predicted to be part of immunoglobulin complex, circulating. Is expressed in several structures, including chorion; fertilized egg; perivitelline fluid; pleuroperitoneal region; and thymus.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
Interactions and Pathways
No data available
Plasmids
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-204F11 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | GenBank:AY643750 (2) | 1459 nt | ||
| Genomic | GenBank:BX649502 | 247387 nt | ||
| Polypeptide | GenPept:AAT67444 (1) | 441 aa |
No data available
- Liu, Y., Lin, S., Wang, C., Li, T., Zheng, G., Sun, W., An, L., Bai, Y., Wu, F. (2024) Sex-Specific Effects of Environmental Exposure to the Antimicrobial Agents Benzalkonium Chloride and Triclosan on the Gut Microbiota and Health of Zebrafish (Danio rerio). Environmental science & technology. 58(35):15450-15462
- Park, G., Foster, C.A., Malone-Perez, M., Hasan, A., Macias, J.J., Frazer, J.K. (2024) Diverse Epithelial Lymphocytes in Zebrafish Revealed Using a Novel Scale Biopsy Method. Journal of immunology (Baltimore, Md. : 1950). 213(12):1902-1914
- Hong, Y., Hu, C.B., Bai, J., Fan, D.D., Lin, A.F., Xiang, L.X., Shao, J.Z. (2023) Essential role of an ERV-derived Env38 protein in adaptive humoral immunity against an exogenous SVCV infection in a zebrafish model. PLoS pathogens. 19:e1011222e1011222
- Rothschild, S.C., Lai, G., Tombes, R.M., Clements, W.K. (2023) Constitutively active CaMKII Drives B lineage acute lymphoblastic leukemia/lymphoma in tp53 mutant zebrafish. PLoS Genetics. 19:e1011102e1011102
- Zhang, C., Zhao, Z., Jia, Y.J., Zhang, P.Q., Sun, Y., Zhou, Y.C., Wang, G.X., Zhu, B. (2023) Rationally Designed Self-Assembling Nanovaccines Elicit Robust Mucosal and Systemic Immunity against Rhabdovirus. ACS applied materials & interfaces. 16(1):228-244
- Fierro-Castro, C., Rotllant, J., Cerdá-Reverter, J.M., Tort, L. (2022) Loss-of-function mutations in melanocortin-1 receptor modulate immune response in teleost fishes. Fish & shellfish immunology. 131:838-846
- Farr, D.A., Nag, D., Withey, J.H. (2021) Characterization of the Immune Response to Vibrio cholerae Infection in a Natural Host Model. Frontiers in cellular and infection microbiology. 11:722520
- Ji, J.F., Hu, C.B., Zhang, N., Huang, X., Shao, T., Fan, D.D., Lin, A.F., Xiang, L.X., Shao, J.Z. (2021) New Insights into IgZ as a Maternal Transfer Ig Contributing to the Early Defense of Fish against Pathogen Infection. Journal of immunology (Baltimore, Md. : 1950). 206(9):2001-2014
- Limonta, G., Mancia, A., Abelli, L., Fossi, M.C., Caliani, I., Panti, C. (2021) Effects of microplastics on head kidney gene expression and enzymatic biomarkers in adult zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 245:109037
- Su, N., Hu, C.B., Shao, T., Jin, C.Y., Li, H., Ji, J.F., Qin, L.L., Fan, D.D., Lin, A.F., Xiang, L.X., Shao, J.Z. (2021) Functional role of CD40 and CD154 costimulatory signals in IgZ-mediated immunity against bacterial infection. Fish and shellfish Immunology reports. 2:100038100038
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