Gene

trim36

ID

ZDB-GENE-040426-2936

Name

tripartite motif containing 36

Symbol

trim36 Nomenclature History

Previous Names

wu:fj48f01
zgc:153447
zgc:63476

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have ubiquitin-protein transferase activity and zinc ion binding activity. Predicted to be involved in regulation of cell cycle. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in anencephaly. Is expressed in nervous system. Orthologous to human TRIM36 (tripartite motif containing 36).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:63476 (7 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With trim36 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
anencephaly	Alliance	?Anencephaly 1	206500

Associated With trim36 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017907	Zinc finger, RING-type, conserved site
Domain	IPR000315	B-box-type zinc finger
Domain	IPR001841	Zinc finger, RING-type
Domain	IPR001870	B30.2/SPRY domain
Domain	IPR003877	SPRY domain
Domain	IPR003879	Butyrophylin-like, SPRY domain
Domain	IPR003961	Fibronectin type III
Domain	IPR017903	COS domain
Domain	IPR027370	Zinc finger, RING-type, eukaryotic
Domain	IPR027726	E3 ubiquitin-protein ligase Trim36, RING finger, HC subclass
Domain	IPR040859	Midline-1, COS domain
Domain	IPR047065	E3 ubiquitin-protein ligase Trim36, B-box-type 2 zinc finger
Domain	IPR047066	E3 ubiquitin-protein ligase Trim36, B-box-type 1 zinc finger
Family	IPR050617	E3 ubiquitin-protein ligases and FN3/SPRY domain-containing proteins
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036116	Fibronectin type III superfamily
Homologous_superfamily	IPR043136	B30.2/SPRY domain superfamily

Domain Details Per Protein

Protein	Length	B30.2/SPRY domain	B30.2/SPRY domain superfamily	B-box-type zinc finger	Butyrophylin-like, SPRY domain	Concanavalin A-like lectin/glucanase domain superfamily	COS domain	E3 ubiquitin-protein ligases and FN3/SPRY domain-containing proteins	E3 ubiquitin-protein ligase Trim36, B-box-type 1 zinc finger	E3 ubiquitin-protein ligase Trim36, B-box-type 2 zinc finger	E3 ubiquitin-protein ligase Trim36, RING finger, HC subclass	Fibronectin type III	Fibronectin type III superfamily	Immunoglobulin-like fold	Midline-1, COS domain	SPRY domain	Zinc finger, RING/FYVE/PHD-type	Zinc finger, RING-type	Zinc finger, RING-type, conserved site	Zinc finger, RING-type, eukaryotic
UniProtKB:A1L1F2 InterPro	721

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	trim36-201 (1) Ensembl	Ensembl	3,446 nt	Select Tool ZFIN BLAST
mRNA	trim36-202 (1) Ensembl	Ensembl	2,214 nt	Select Tool ZFIN BLAST
mRNA	trim36-204 (1) Ensembl	Ensembl	776 nt	Select Tool
mRNA	trim36-205 (1) Ensembl	Ensembl	878 nt	Select Tool
mRNA	trim36-206 (1) Ensembl	Ensembl	1,326 nt	Select Tool
ncRNA	trim36-004 (1) Ensembl	Ensembl	590 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations